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Pure red cell aplasia
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Pure red cell aplasia : ウィキペディア英語版
Pure red cell aplasia

Pure red cell aplasia (PRCA) or erythroblastopenia refers to a type of anemia affecting the precursors to red blood cells but not to white blood cells. In PRCA, the bone marrow ceases to produce red blood cells. The condition has been first described by Paul Kaznelson in 1922.
==Causes==
Causes include:
* Autoimmune disease.
* Thymoma.
* Viral infections such as HIV, herpes, parvovirus B19 (Fifth disease), or hepatitis.
* Lymphoproliferative. Association of pure red cell aplasia with T large granular lymphocyte leukemia is well recognized, especially in China.
* Idiopathic. Many cases of PRCA are considered idiopathic in that there is no discernible cause detected.
* Drugs such as mycophenolic acid〔Petrochko C (2009). ("FDA Strengthens Warning on Transplant Drug." ) ''Medpage Today.'' 14 August 2009. Accessed on 19 August 2009.〕 or erythropoietin.
* Congenital. The term "hereditary pure red cell aplasia" has been used to refer to Diamond-Blackfan anemia.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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